Dadang Mulya, 6 Tahun Jadi Model Di Bungkus Rokok Indonesia Ini Tuntut Royalti, Kisahnya Bikin Nyesek!
Beritaterheboh.com - Dadang Mulya (42) warga Kabupaten Kuningan, Jawa Barat mengaku sebagai pria yang tengah merokok sembari menggendong bayi di kemasan rokok. Dadang sempat memprotes dan menuntut royalti.
Dadang tercatat sebagai warga Desa Pancalang, Kecamatan Pancalang, Kabupaten Kuningan. Ayah empat ini ini mengaku kaget saat pertama kali melihat fotonya yang tengah merokok sembari menggendong anak itu muncul di kemasan rokok pada 2012 silam.
Dadang menyatakan tak pernah mengeluarkan izin atau persetujuan kepada siapapun. Namun Dadang merasa yakin, foto yang terpasang di kemasan rokok itu merupakan fotonya saat menggendong anak keduanya, Rizki Indriawan.
"Enam tahun lalu, saya pernah difoto sama orang saat menonton bola di lapangan bola Desa Pancalang. Saat itu saya sedang menggendong anak saya, sambil rokok," ucap Dadang saat ditemui detikcom di Padepokan Anti Galau milik Ustaz Ujang Bustomi di Desa Sinarancang, Kecamatan Mundu, Kabupaten Cirebon, Jawa Barat, Selasa (24/7/2018).
Dadang menceritakan awalnya sebuah mobil melintas dan berhenti di depannya. Sekitar 10 menit setelah berhenti, dikatakan Dadang, salah seorang keluar dari mobil dan memotretnya.
"Saya cerita ke istri soal kejadian itu, kata istri tidak apa-apa. Awalnya juga saya pikir itu motret orang lain, tapi di belakang saya tidak ada orang, saya sadar kalau orang tadi motret saya," ucapnya.
Sebulan kemudian, usai kejadian itu wajah Dadang muncul di kemasan rokok. Dadang mulai kepikiran. Lagi, Dadang pun menceritakan kepada istrinya, Mimin (37). Mimin menanggapinya dengan santai.
"Istri saya juga bilangnya tidak apa-apa," ujar Dadang.
Pria yang bekerja sebagai buruh serabutan itu masih kepikiran. Dadang kerap bercerita dan mengadu ke tetangga dan orang terdekatnya tentang fotonya yang ada di kemasan rokok.
"Ya banyak yang tidak percaya. Minggu lalu saya cerita lagi dengan sahabat saya, dia percaya katanya suruh mengadu ke desa," ucap Dadang.
Dadang pun menuruti saran sahabatnya itu. Namu, pihak desa menyarankan Dadang untuk berkonsultasi dengan pihak kepolisian. "Sahabat saya menyarankan untuk lapor kembali ke pihak desa. Saya nurut, terus diarahkan ke polsek, dan diarahkan ke Badan Penyelesaian Sengketa Konsumen (BPSK). Terus jadi ramai," katanya.
Enggan Menempuh jalur hukum
Senin (23/7/2018), Dadang mendatangi kantor Badan Penyelesaian Sengketa Konsumen (BPSK) Kabupaten Kuningan. Dadang pun mempertanyakan tentang penggunaan fotonya yang tanpa izin itu ke BPSK, serta menuntut royalti. Namun, BPSK Kuningan menyarankan Dadang untuk membuat laporan ke pihak kepolisian. Lantaran kasus Dadang tersebut bukan termasuk sengketa konsumen.
Dadang pun melanjutkan langkahnya dan bertemu dengan Dudung Hidayat, yang ditunjuk sebagai kuasa hukumnya. Keesokan harinya, Selasa (24/7/2018), Dadang menandatangani surat kuasa untuk Dudung Hidayat. Beberapa jam setelah menandatangani surat kuasa, Dadang bertemu dengan Nana Mulyana Latief, orang yang mengaku menyekolahkan anak pertama Dadang, Aditya Prabowo (16) ke SMK.
Dadang yang sebelumnya memprotes dan meminta royalti terkait penggunaan fotonya yang tanpa izin itu berubah pikiran. Dadang mengurungkan niatnya untuk mengambil langkah hukum. Dadang mencabut surat kuasa terhadap Dudung Hidayat.
"Tadi pagi disuruh tanda tangan surat (surat kuasa) yang ditunjukkan oleh pesuruh kuasa hukum. Saya nurut tanda tangan. Saya tidak mengerti soal hukum, tidak mengerti apa-apa. Sekitar pukul 10.00 WIB tadi saya sudah tanda tangan untuk mencabut surat kuasa," kata Dadang saat ditemui detikcom di Padepokan Anti Galau milik Ustaz Ujang Bustomi di Desa Sinarancang, Kecamatan Mundu, Kabupaten Cirebon, Jawa Barat, Selasa (24/7/2018).
Dadang mengatakan alasannya mencabut kembali surat kuasa itu karena tak ingin memperpanjang masalah ini. Dadang hanya meminta kejelasan dan perhatian dari pemerintah dan produsen rokok. "Ya kalau saya pribadi sih hanya minta perhatian saja. Tidak lebih dari itu," ucap Dadang.
Dadang mengaku diimpit masalah ekonomi yang sulit. Dalam kesehariannya, Dadang bekerja sebagai buruh serabutan dengan penghasilan di bawah Rp 70.000 per hari.
"Tidak setiap hari ada kerjaan. Ya pernah tidak dapat uang seharian karena tidak kerja, tapi keluarga kami selalu mengajarkan untuk bersyukur," ucapnya.
Focusing on the body's organic clock might be a potential technique for treating disease, another examination appears. Two exacerbates that objective segments of the circadian clock executed a few sorts of disease cells in the lab and impeded the development of mind tumors in mice without hurting sound cells, the examination specialists revealed.
In lab tests and in mice, the treatment likewise murdered a kind of senescent cells—precancerous cells that have quit becoming because of a malignancy causing change.
The circadian clock directs many organic capacities, from rest examples to cell division. By focusing on parts of the clock apparatus, the mixes control two capacities that growth and senescent cells need to survive, the specialists found. The NCI-supported examination was distributed January 18 in Nature.
"This investigation features how circadian rhythms and tumor science cross, how imperative these two fields are to each other, and how we may start to misuse that relationship to target malignancies," said Joanna Watson, Ph.D., a program executive in NCI's Division of Cancer Biology, who was not associated with the examination.
The examination specialists plan to build up a medication like the considered mixes to treat people and accept there are numerous potential applications for such a treatment.
"We have discovered a totally new class of targets, so the alternatives are boundless," said the examination's senior agent Satchidananda Panda, Ph.D., an educator at the Salk Institute.
The Rhythm of the Circadian Clock
The circadian clock is a complex natural hardware that controls the day by day cadence of capacities, for example, rest, body temperature, and assimilation. The ace "clock" is a territory in the cerebrum that faculties natural signs, (for example, light) and imparts data to optional checks in different organs.
Likewise, every cell in the body contains its own particular clock that controls the day by day wavering of numerous phone capacities. All checks in the body are for the most part in a state of harmony, enabling the life form to adjust to its condition and keep up a natural adjust.
The circadian clock controls the "on" and "off" cycling of numerous capacities that are imperative for malignancy advancement. Interruption of the clock may make these capacities stall out "on" or "off," making the correct conditions for tumors to create and develop, Dr. Panda clarified. Concentrates by his gathering and others have demonstrated that the initial phase in growth improvement upsets circadian rhythms.
REV-ERB proteins are key segments of the clock apparatus that quell organic capacities that disease cells rely upon, for example, cell division and cell digestion. So Dr. Panda and his partners chose to research whether intensifies that initiate REV-ERBs (known as REV-ERB agonists) may have the capacity to execute tumor cells by blocking capacities they have to keep developing.
In lab tests, the scientists found that two REV-ERB agonists slaughtered diverse sorts of disease cells (counting cerebrum, colon, and bosom), despite the fact that the cells had distinctive hereditary changes that drive malignancy development. The REV-ERB agonists did not execute solid cerebrum or skin cells, be that as it may.
These discoveries recommend that medications that initiate REV-ERBs possibly could be utilized to treat a wide range of sorts of malignancy, the scientists clarified.
"That at first shocked us since it is exceptionally uncommon to discover such flexibility in a solitary medication," said lead specialist Gabriele Sulli, Ph.D., additionally of the Salk Institute. Be that as it may, when the scientists found how the REV-ERB agonists execute cells, it progressed toward becoming clearer why these mixes influence such huge numbers of kinds of growth cells.
Kicking Cancer Where It Hurts
In spite of the fact that REV-ERB proteins control a few natural capacities, the specialists found that the agonists square two particular pathways. One, called autophagy, is a reusing like process that debases pointless, harmed, and dangerous particles to produce supplements. The other pathway is the amalgamation of fats called lipids.
Both lipid union and autophagy give building squares to make new cells. Sound cells require just low levels of these pathways, however tumor cells depend on them intensely in light of the fact that they are continually isolating.
"So it bodes well that the impact of the medication is autonomous of the sort of growth and the instrument that is driving persistent cell expansion," Dr. Panda said.
Past research has demonstrated that, in mice, one of the two REV-ERB agonists utilized as a part of this investigation can cross the blood-mind hindrance, a limit that regularly keeps drugs from achieving the cerebrum. Furthermore, when Dr. Sulli and his partners broke down information from NCI's REMBRANDT (Repository of Molecular Brain Neoplasia Data) information entry, they found that, among individuals with a kind of mind malignancy called glioblastoma, those with larger amounts of REV-ERBs lived longer than those with low levels.
In light of these discoveries, the scientists tried their approach in two mouse models of mind growth. Treatment with the agonist lessened autophagy, executed glioblastoma cells, decreased tumor development, and expanded survival superior to anything a control compound.
Essentially, the scientists did not watch any indications of harmful symptoms in mice treated with the agonist.
The Danger of Senescent Cells
Dr. Sulli and his associates likewise thought about whether the REV-ERB agonists may slaughter different cells that rely upon autophagy and have disturbed circadian rhythms. Senescent cells—which quit developing to avoid disease arrangement—fit the bill.